R. Schmouder: search on Z-Library

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1

Pharmacodynamics, pharmacokinetics, and safety of multiple doses of FTY720 in stable renal transplant patients: a multicenter, randomized, placebo-controlled, phase I study

Kahan, Barry D., Karlix, Janet L., Ferguson, Ronald M., Leichtman, Alan B., Mulgaonkar, Shamkant, Gonwa, Thomas A., Skerjanec, Andrej, Schmouder, Robert L., Chodoff, Lawrence

Journal:

Transplantation Journal

Year:

2003

Language:

english

File:

PDF, 352 KB

english, 2003

2

Fingolimod (FTY720): discovery and development of an oral drug to treat multiple sclerosis

Brinkmann, Volker, Billich, Andreas, Baumruker, Thomas, Heining, Peter, Schmouder, Robert, Francis, Gordon, Aradhye, Shreeram, Burtin, Pascale

Journal:

Nature Reviews Drug Discovery

Year:

2010

Language:

english

File:

PDF, 649 KB

english, 2010

3

The effect on heart rate of combining single-dose fingolimod with steady-state atenolol or diltiazem in healthy subjects

John M. Kovarik, Michael Lu, Gilles-Jacques Riviere, Irene Barbet, Steve Maton, D. Ronald Goldwater, Robert L. Schmouder

Journal:

European Journal of Clinical Pharmacology

Year:

2008

Language:

english

File:

PDF, 142 KB

english, 2008

4

Overview of FTY720 Clinical Pharmacokinetics and Pharmacology

Kovarik, John M., Schmouder, Robert L., Slade, Alan J.

Journal:

Therapeutic Drug Monitoring

Year:

2004

Language:

english

File:

PDF, 86 KB

english, 2004

5

Can Disproportionality Analysis of Post-marketing Case Reports be Used for Comparison of Drug Safety Profiles?

Michel, Christiane, Scosyrev, Emil, Petrin, Michael, Schmouder, Robert

Journal:

Clinical Drug Investigation

Year:

2017

Language:

english

File:

PDF, 650 KB

english, 2017

6

Interferon-γ regulation of human renal cortical epithelial cell-derived monocyte chemotactic peptide-1

Schmouder, Robert L, Strieter, Robert M, Kunkel, Steven L

Journal:

Kidney International

Year:

1993

Language:

english

File:

PDF, 686 KB

english, 1993

7

Hyperkinetic borderline hypertension in Tecumseh, Michigan

Julius, Stevo, Krause, Lisa, Schork, Nicholas J., Mejia, Agnes D., Jones, Kerin A., van de Ven, Cosmas, Johnson, Ernest H., Sekkarie, M. Abed, Kjeldsen, Sverre Erik, Petrin, Jurij, Schmouder, Robert,

Journal:

Journal of Hypertension

Year:

1991

File:

PDF, 684 KB

1991

8

FTV 720A mediates reduction of lymphocyte counts in human renal allograft recipients by an apoptosis-independent mechanism

T. Böhler, J. Waiser, M. Schütz, M. Friedrich, R. Schötschel, S. Reinhold, R. Schmouder, K. Budde, H.-H. Neumayer

Journal:

Transplant International

Year:

2000

Language:

english

File:

PDF, 240 KB

english, 2000

9

Fingolimod (FTY720) in Severe Hepatic Impairment: Pharmacokinetics and Relationship to Markers of Liver Function

Kovarik, John M., Schmouder, Robert L., Hartmann, Stefan, Riviere, Gilles-Jacques, Picard, Franck, Voss, Brigitta, Weiss, Markus, Wagner, Frank, Schmidt, Hartmut H.-J.

Journal:

Journal of Clinical Pharmacology

Year:

2006

Language:

english

File:

PDF, 129 KB

english, 2006

10

Next-generation biomarkers for detecting kidney toxicity

Bonventre, Joseph V, Vaidya, Vishal S, Schmouder, Robert, Feig, Peter, Dieterle, Frank

Journal:

Nature Biotechnology

Year:

2010

Language:

english

File:

PDF, 391 KB

english, 2010

11

Pharmacodynamic Effects of Steady-State Fingolimod on Antibody Response in Healthy Volunteers: A 4-Week, Randomized, Placebo-Controlled, Parallel-Group, Multiple-Dose Study

Boulton, Craig, Meiser, Karin, David, Olivier J., Schmouder, Robert

Journal:

Journal of Clinical Pharmacology

Year:

2012

Language:

english

File:

PDF, 1005 KB

english, 2012

12

Randomized calcineurin inhibitor cross over study to measure the pharmacokinetics of co-administered enteric-coated mycophenolate sodium

Bruce Kaplan, Herwig-Ulf Meier-Kriesche, Paula Minnick, Marie-Claude Bastien, Romain Sechaud, Ching-Ming Yeh, Sebastien Balez, Franck Picard, Robert Schmouder

Journal:

Clinical Transplantation

Year:

2005

Language:

english

File:

PDF, 191 KB

english, 2005

13

FTY720 AND LYMPHOCYTE COUNT: ETHNIC DIVERSITY NOT A FACTOR IN DYNAMIC RESPONSE

Slade, A J., Kovarik, J M., Yokoi, A, Shishido, A, Mee-Lee, D, Schmouder, R

Journal:

Transplantation Journal

Year:

2004

Language:

english

File:

PDF, 442 KB

english, 2004

14

Pharmacokinetics, pharmacodynamics, safety, and tolerability of single-dose fingolimod (FTY720) in adolescents with stable renal transplants

R. Ettenger, R. Schmouder, J. M. Kovarik, M. C. Bastien, P. F. Hoyer

Journal:

Pediatric Transplantation

Year:

2011

Language:

english

File:

PDF, 248 KB

english, 2011

15

In vitro and in vivo interleukin-8 production in human renal cortical epithelia

Schmouder, Robert L, Strieter, Robert M, Wiggins, Roger C, Chensue, Stephen W, Kunkel, Steven L

Journal:

Kidney International

Year:

1992

Language:

english

File:

PDF, 870 KB

english, 1992

16

Mycophenolic Acid Metabolite Profile in Renal Transplant Patients Receiving Enteric-Coated Mycophenolate Sodium or Mycophenolate Mofetil

H. Tedesco-Silva, M.-C. Bastien, L. Choi, C. Felipe, J. Campestrini, F. Picard, R. Schmouder

Journal:

Transplantation Proceedings

Year:

2005

Language:

english

File:

PDF, 95 KB

english, 2005

17

FTY720 Pharmacokinetics in Mild to Moderate Hepatic Impairment

Kovarik, J. M., Schmouder, R. L., Serra, D., Wang, Y., Wiegand, H., Dilzer, S. C., Lasseter, K. C.

Journal:

Journal of Clinical Pharmacology

Year:

2005

Language:

english

File:

PDF, 117 KB

english, 2005

18

Hyperkinetic borderline hypertension in Tecumseh, Michigan

Julius, Stevo, Krause, Lisa, Schork, Nicholas J., Mejia, Agnes D., Jones, Kerin A., van de Ven, Cosmas, Johnson, Ernest H., Sekkarie, M. Abed, Kjeldsen, Sverre Erik, Petrin, Jurij, Schmouder, Robert,

Journal:

Journal of Hypertension

Year:

1991

File:

PDF, 684 KB

1991

19

The Rebirth of Progesterone in the Prevention of Preterm Labor

Schmouder, V. M., Prescott, G. M., Franco, A., Fan-Havard, P.

Journal:

Annals of Pharmacotherapy

Year:

2013

Language:

english

File:

PDF, 162 KB

english, 2013

20

High blood pressure in older Americans. The First National Health and Nutrition Examination Survey.

Harlan, W. R., Hull, A. L., Schmouder, R. L., Landis, J. R., Larkin, F. A., Thompson, F. E.

Journal:

Year:

1984

Language:

english

File:

PDF, 354 KB

english, 1984

21

EPITHELIAL-DERIVED NEUTROPHIL-ACTIVATING FACTOR-78 PRODUCTION IN HUMAN RENAL TUBULE EPITHELIAL CELLS AND IN RENAL ALLOGRAFT REJECTION

Schmouder, Robert L., Strieter, Robert M., Walz, Alfred, Kunkel, Steven L.

Journal:

Transplantation Journal

Year:

1995

File:

PDF, 687 KB

1995

22

Pharmacokinetic Interaction Between Fingolimod and Carbamazepine in Healthy Subjects

David, Olivier J., Behrje, Rhett, Pal, Parasar, Hara, Hisanori, Lates, Christian D., Schmouder, Robert

Journal:

Clinical Pharmacology in Drug Development

Year:

2018

Language:

english

File:

PDF, 750 KB

english, 2018

23

Administration diluents differentiate Neoral from a generic cyclosporine oral solution

John M Kovarik, Denise Barilla, Louis McMahon, Yibin Wang, James Kisicki, Robert Schmouder

Journal:

Clinical Transplantation

Year:

2002

Language:

english

File:

PDF, 124 KB

english, 2002

24

Immunosuppressive therapies for the twenty-first century

Journal:

Transplantation Proceedings

Year:

2000

Language:

english

File:

PDF, 87 KB

english, 2000

25

SAFETY AND PHARMACODYNAMICS OF MULTIPLE DOSES OF FTY720.

Kahan, Barry D., Chodoff, Lawrence, Leichtman, Alan B., Karlix, Janet L., Ferguson, Ronald M., Dehlinger, Jennifer, Schmouder, Robert L., Maher, Thomas, DʼSilva, Milbhor, Sablinski, Tomasz

Journal:

Transplantation Journal

Year:

2000

File:

PDF, 926 KB

2000

26

FTY720, a Novel Immunomodulator in de Novo Kidney Transplant Patients: Pharmacokinetics and Exposure-Response Relationship

Skerjanec, Andrej, Tedesco, Helio, Neumayer, Hans-H., Cole, Edward, Budde, Klemens, Hsu, Chyi-Hung, Schmouder, Robert

Journal:

Journal of Clinical Pharmacology

Year:

2005

Language:

english

File:

PDF, 299 KB

english, 2005

27

STEADY-STATE PHARMACOKINETICS OF ENTERIC-COATED MYCOPHENOLATE SODIUM (MYFORTIC®) IN STABLE RENAL TRANSPLANT PATIENTS DIFFER DURING CONCOMITANT TREATMENT WITH NEORAL® OR TACROLIMUS

Kaplan, B, Bastien, M-C, Meier-Kriesche, U, Minnick, P, Sechaud, R, Yeh, C-M, Balez, S, Picard, F, Schmouder, R

Journal:

Transplantation Journal

Year:

2004

Language:

english

File:

PDF, 946 KB

english, 2004

28

The cytokine response in renal allograft rejection

Schmouder, R. L., Kunkel, S. L.

Journal:

Nephrology Dialysis Transplantation

Year:

1995

Language:

english

File:

PDF, 921 KB

english, 1995

29

BLOOD PRESSURE AND NUTRITION IN ADULTS THE NATIONAL HEALTH AND NUTRITION EXAMINATION SURVEY1

HARLAN, WILLIAM R., HULL, ALAN L., SCHMOUDER, ROBERT L., LANDIS, J. RICHARD, THOMPSON, FRANCES E., LARKIN, FRANCES A.

Journal:

American Journal of Epidemiology

Year:

1984

Language:

english

File:

PDF, 808 KB

english, 1984

30

Oral-intravenous crossover study of fingolimod pharmacokinetics, lymphocyte responses and cardiac effects

John M. Kovarik, Stefan Hartmann, Michael Bartlett, Gilles-Jacques Riviere, Daniel Neddermann, Yibin Wang, Andreas Port, Robert L. Schmouder

Journal:

Biopharmaceutics & Drug Disposition

Year:

2007

Language:

english

File:

PDF, 124 KB

english, 2007

31

Chronopharmacokinetics of Mycophenolic Acid and Its Glucuronide and Acyl Glucuronide Metabolites in Kidney Transplant Recipients Converted From Cyclosporine to Everolimus

Tedesco-Silva, Helio, Rosso Felipe, Claudia, Slade, Alan, Schmouder, Robert L., Medina Pestana, Jose Osmar

Journal:

Therapeutic Drug Monitoring

Year:

2012

Language:

english

File:

PDF, 316 KB

english, 2012

32

MYCOPHENOLIC ACID METABOLITE PROFILE IN RENAL TRANSPLANT PATIENTS RECEIVING ENTERIC-COATED MYCOPHENOLATE SODIUM (EC-MPS, MYFORTIC®)

Tedesco-Silva, H, Bastien, M -C., Choi, L, Felipe, C, Campestrini, J, Picard, F, Schmouder, R

Journal:

Transplantation Journal

Year:

2004

Language:

english

File:

PDF, 442 KB

english, 2004

33

Lumiracoxib Does Not Affect the Ex Vivo Antiplatelet Aggregation Activity of Low-Dose Aspirin in Healthy Subjects

Jermany, J., Branson, J., Schmouder, R., Guillaume, M., Rordorf, C.

Journal:

Journal of Clinical Pharmacology

Year:

2005

Language:

english

File:

PDF, 140 KB

english, 2005

34

Platelet sodium-proton exchange is increased in essential hypertension

Schmouder, Robert L., Weder, Alan B.

Journal:

Journal of Hypertension

Year:

1989

File:

PDF, 615 KB

1989

35

NVP-AEB071: EFFECT OF MILD AND MODERATE HEPATIC IMPAIRMENT ON AEB071 PHARMACOKINETICS

Slade, A, Liu, C, Kovarik, J M., Dumortier, T, Preston, R, Schmouder, R

Journal:

Transplantation Journal

Year:

2008

Language:

english

File:

PDF, 301 KB

english, 2008

36

FTY720: Placebo-Controlled Study of the Effect on Cardiac Rate and Rhythm in Healthy Subjects

Schmouder, Robert, Serra, Denise, Wang, Yibin, Kovarik, John M., DiMarco, John, Hunt, Thomas L., Bastien, Marie-Claude

Journal:

Journal of Clinical Pharmacology

Year:

2006

Language:

english

File:

PDF, 237 KB

english, 2006

37

The ability of atropine to prevent and reverse the negative chronotropic effect of fingolimod in healthy subjects

John M. Kovarik, Alan Slade, Gilles-Jacques Riviere, Daniel Neddermann, Steve Maton, Thomas L. Hunt, Robert L. Schmouder

Journal:

British Journal of Clinical Pharmacology

Year:

2008

Language:

english

File:

PDF, 653 KB

english, 2008

38

HIGH DOSE FTY720: LYMPHOCYTE RESPONSE AT SINGLE DOSES UP TO 40 MG

Slade, A J., Kovarik, J M., Hunt, T L., Schmouder, R

Journal:

Transplantation Journal

Year:

2004

Language:

english

File:

PDF, 447 KB

english, 2004

39

Effect of multiple-dose erythromycin on everolimus pharmacokinetics

J.M. Kovarik, D. Beyer, M.N. Bizot, Q. Jiang, M. Shenouda, R.L. Schmouder

Journal:

European Journal of Clinical Pharmacology

Year:

2005

Language:

english

File:

PDF, 224 KB

english, 2005

40

Ketoconazole Increases Fingolimod Blood Levels in a Drug Interaction via CYP4F2 Inhibition

Kovarik, John M., Dole, Kiran, Riviere, Gilles-Jacques, Pommier, Francoise, Maton, Steve, Jin, Yi, Lasseter, Kenneth C., Schmouder, Robert L.

Journal:

Journal of Clinical Pharmacology

Year:

2009

Language:

english

File:

PDF, 770 KB

english, 2009

41

Pharmacodynamics of Single Doses of the Novel Immunosuppressant FTY720 in Stable Renal Transplant Patients

Klemens Budde, Robert L. Schmouder, Bjorn Nashan, Reinhard Brunkhorst, Peter W. Lücker, Thomas Mayer, Laurence Brookman, Jerry Nedelman, Andrej Skerjanec, Torsten Böhler, Hans-Hellmut Neumayer

Journal:

American Journal of Transplantation

Year:

2003

Language:

english

File:

PDF, 137 KB

english, 2003

42

Pharmacokinetic/pharmacodynamic relationships of FTY720 in kidney transplant recipients

Park, S.I., Felipe, C.R., Machado, P.G., Garcia, R., Skerjanec, A., Schmouder, R., Tedesco-Silva Jr., H., Medina-Pestana, J.O.

Journal:

Brazilian Journal of Medical and Biological Research

Year:

2005

Language:

english

File:

PDF, 813 KB

english, 2005

43

Pharmacokinetic interaction between verapamil and everolimus in healthy subjects

J. M. Kovarik, D. Beyer, M. N. Bizot, Q. Jiang, M. J. Allison, R. L. Schmouder

Journal:

British Journal of Clinical Pharmacology

Year:

2005

Language:

english

File:

PDF, 112 KB

english, 2005

44

Placebo-controlled study of the effects of fingolimod on cardiac rate and rhythm and pulmonary function in healthy volunteers

Robert Schmouder, Sam Hariry, Olivier J. David

Journal:

European Journal of Clinical Pharmacology

Year:

2012

Language:

english

File:

PDF, 263 KB

english, 2012

45

Population Pharmacokinetics of Fingolimod Phosphate in Healthy Participants

Wu, Kai, Mercier, Francois, David, Olivier J., Schmouder, Robert L., Looby, Michael

Journal:

Journal of Clinical Pharmacology

Year:

2012

Language:

english

File:

PDF, 472 KB

english, 2012

46

Determination of Seminal Concentration of Fingolimod and Fingolimod-Phosphate in Multiple Sclerosis Patients Receiving Chronic Treatment With Fingolimod

David, Olivier J., Berwick, Amy, Pezous, Nicole, Lang, Michael, Tiel-Wilck, Klaus, Ziemssen, Tjalf, Li, Peng, Hara, Hisanori, Schmouder, Robert

Journal:

Clinical Pharmacology in Drug Development

Year:

2017

Language:

english

File:

PDF, 92 KB

english, 2017

47

Differentiation of innovator versus generic cyclosporine via a drug interaction on sirolimus

John M. Kovarik, Adele Noe, Yibin Wang, Irene Mueller, Gilberto DeNucci, Robert L. Schmouder

Journal:

European Journal of Clinical Pharmacology

Year:

2006

Language:

english

File:

PDF, 117 KB

english, 2006

48

NVP-AEB071 PHARMACOKINETICS: EFFECT OF METABOLIC INHIBITION WITH KETOCONAZOLE

Slade, A, Kovarik, J M., Huang, A, Chandler, P, Schmouder, R

Journal:

Transplantation Journal

Year:

2008

Language:

english

File:

PDF, 144 KB

english, 2008

49

FTY 720A mediates reduction of lymphocyte counts in human renal allograft recipients by an apoptosis-independent mechanism

T. Böhler, J. Waiser, M. Schütz, M. Friedrich, R. Schötschel, S. Reinhold, R. Schmouder *, ‡ , K. Budde, H.-H. Neumayer

Journal:

Transplant International

Year:

2000

Language:

english

File:

PDF, 58 KB

english, 2000

50

Single-dose FTY720 pharmacokinetics, food effect, and pharmacological responses in healthy subjects

John M. Kovarik, Robert Schmouder, Denise Barilla, Yibin Wang, Gerolf Kraus

Journal:

British Journal of Clinical Pharmacology

Year:

2004

Language:

english

File:

PDF, 117 KB

english, 2004

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